VIPomaFrom Wikipedia, the free encyclopediaJump to: navigation, search
A VIPoma (also known as Verner Morrison syndrome, after the physicians who first described it [1]) is a rare (1 per 10,000,000 per year) endocrine tumor,[2] usually (about 90%) originating in the pancreas, that produces vasoactive intestinal peptide (VIP).
A syndrome caused by non-β islet cell tumors. It may be associated with multiple endocrine neoplasia type 1.
The massive amounts of VIP in turn cause profound and chronic watery diarrhea and resultant dehydration, hypokalemia, achlorhydria (hence WDHA-syndrome, or pancreatic cholera syndrome), acidosis, vasodilation (flushing and hypotension), hypercalcemia and hyperglycemia.[3]
댓글 없음:
댓글 쓰기